Associate Professor of Bacterial Pathogenesis & Metabolism
The research carried out by my group addresses important questions in both medical and environmental microbiology.
In Salmonella, we are interested in elucidating the regulatory pathways activated under conditions which cause damage to the outer membrane. These envelope stress response (ESR) regulators are critical for pathogenesis and resisting antibiotics.
Using Paracoccus denitrificans as a model bacterial denitrifer, our team have been filling the large gaps in regulation of denitrification including the role of bacterial small RNAs (sRNAs). We provided the first evidence that manipulation of sRNA expression impacts the rate of denitrification and net nitrous oxide emissions. Through our current UKRI funded projects we aim to overhaul the mechanistic understanding of the regulation of denitrification and the contribution of sRNAs to this process.