Dr Gwenaelle Le Gall

Biography

My focus is to use metabolomics and lipidomics to study human metabolism and contribute to research in human nutrition and disease prevention. I believe that establishing links between fluid/tissue metabolites and disease is one of the first steps to understand the mechanisms involved in disease progression.

Equally important is the screening for biomarkers in large sets of samples as getting insight in the profile heterogeneity of the human population could contribute to the prevention/delay of chronic diseases.

I have expertise in metabolomics/lipidomics and over 25 years expertise in the field of metabolite analysis using techniques such as Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS).

My knowledge extends to mammalian, food, plant and microbial metabolism. I have worked on numerous projects covering human nutrition and health, food authenticity, bacterial substrate specificity and the interactions between the host and the microbiota. I am an author or co-author of over 80 peer-reviewed articles, as well as numerous conference proceedings, posters and book chapters.

Key words: Metabolomics, quantification, NMR, MS, polar compounds, lipidomics, bile acids, dietary and microbial phenolic compounds, amino acids and products, TCA cycle intermediates, sugars, biogenic amines, tryptophan pathways, short chain fatty acids